Diaphragm valves provide exceptional cleanability, drainability, and product isolation, making them the preferred choice for biopharmaceutical, animal health, and high-purity systems. Their design eliminates internal pockets where product can become trapped. ITT’s Pure-Flo® and EnviZion® designs take this further by offering optimized flow paths and enhanced sealing technologies that support demanding hygienic standards.

Engineered for Hygienic Performance
ITT Pure-Flo® and EnviZion® diaphragm valves set the standard for hygienic processing, offering exceptional cleanability, drainability, and long-term reliability across pharmaceutical, biotech, animal health, and other high-purity applications.
With tool-less maintenance, rapid diaphragm changeouts, and designs that minimize deadlegs and entrapment areas, these valves deliver consistent performance while reducing downtime. Williams-Carver proudly supplies and supports the full ITT diaphragm valve portfolio, helping customers achieve higher efficiency and confidence in every process line.
Diaphragm Valve Overview

ITT Pure-Flo High Purity Diaphragm Valves
ITT Pure-Flo diaphragm valves are engineered specifically for high-purity biopharmaceutical and hygienic processing applications, offering exceptional cleanability, drainability, and process control. Their proven design provides reliable sealing, reduced hold-up volume, and compatibility with the demanding standards of modern drug, vaccine, and sterile manufacturing. Pure-Flo remains one of the most trusted and widely specified valve lines in the industry.

ITT EnviZion High Purity Diaphragm Valves
The ITT EnviZion valve series introduces breakthrough mount-and-turn technology that enables tool-less diaphragm replacement in under three minutes, dramatically reducing maintenance time. Its active thermal compensation system maintains a consistent seal without re-torquing, even under extreme temperature cycling. EnviZion delivers superior reliability, cleanability, and long-term performance for the most demanding bioprocessing environments.

ITT Valve Instrumentation & Controls
ITT’s instrumentation and control offerings provide advanced monitoring, automation, and feedback for Pure-Flo and EnviZion valves. The Integrated Sensing Platform (ISP) delivers accurate, network-ready valve position feedback with auto-calibration and durable washdown-rated construction. Additional controls, including 73 Series positioners and pneumatic actuation options, ensure precise, repeatable valve operation across complex processing systems.

ITT Diaphragms
ITT Engineered Valves offers high-performance diaphragms designed for long life, reliability, and compliance in pharmaceutical and bioprocessing applications. Their modified PTFE diaphragm provides superior resistance to aggressive SIP/CIP cycles, while Grade E1 EPDM delivers excellent elasticity, sealing, and durability.
For EnviZion valves, diaphragm changeout is fast and repeatable thanks to the toolless mount-and-turn design—reducing maintenance time dramatically. All diaphragm materials are USP-compliant, fully traceable, and available in multiple elastomers including Buna, butyl, and enhanced PTFE-backed options.
Frequently Asked Questions
The diaphragm is the primary sealing element, so its material and design directly affect longevity, cleanability, and overall valve function. ITT Pure-Flo® diaphragms undergo rigorous testing and traceability controls, while EnviZion® diaphragms incorporate advanced sealing features that maintain consistent compression without retorquing, even through repeated thermal cycles.
Traditional designs require multiple fasteners, tools, and precise retorquing to maintain an effective seal. The ITT EnviZion® valve revolutionizes this with a tool-less, mount-and-turn design that reduces diaphragm replacement from roughly 20–25 minutes to under 3 minutes while delivering long-term sealing stability using active thermal compensation. This ensures faster maintenance and more consistent system performance.


