ITT Pure-Flo Diaphragm Valves

ITT Pure-Flo High Purity Diaphragm Valves

Key Features & Benefits:

• ITT Pure-Flo offers one of the most complete and versatile families of high-purity diaphragm valves in the sanitary processing industry, engineered for cleanability, reliability, and simplified system design. Their valve bodies cover a broad spectrum of applications — from basic flow control to complex multi-path processing systems.
  • Engineered for cleanability & drainability
  • Industry proven high-purity diaphragm technology
  • Bonnet isolation: isolating working parts of valve from process fluids
  • Precision manufacturing ensures reliable sealing
  • Full traceability for regulatory compliance
  • Long diaphragm life reduces maintenance frequency

Valve Body Types & Applications:

• 2-Way (Standard) Diaphragm Valves
  • These are basic on/off or throttling valves. A flexible diaphragm seals over a weir or seat, isolating the process fluid from the actuator and sealing surfaces. When opened, fluid flows through a smooth, unobstructed path; when closed, the diaphragm presses against the seat to stop flow — ideal for clean/process lines and utility fluids.
• Zero-Static / Point-of-Use Valves
  • Designed to eliminate dead legs and stagnation — critical for sterile water, WFI, or pharmaceutical process lines. The valve’s weir is integrated inline so the flow passes through without creating a pocket where fluid can sit, minimizing microbial risk and improving system sanitation. These valves also support sampling, draining, or purge operations while still complying with stringent hygienic standards.
• Integral Sterile-Access / Sampling & Purge Valves
  • For applications requiring sterile sampling, purging, or isolation, Pure-Flo offers valve bodies that combine the main flow path with a secondary access port — all in one integrated valve block. This design reduces flange count, lowers hold-up volume, and simplifies system layouts while allowing safe, sanitary access for sampling or cleaning operations.
• Multi-Port / Block-Body Valves
  • For complex processing demands — such as mixing, diversion, feed/discharge configurations, or utility distribution — Pure-Flo’s block-body valves combine multiple valve elements into a single stainless steel block. This reduces overall system footprint, minimizes dead legs for higher product purity, minimizes welded joints and potential leak points, lowers hold-up volume, and enhances cleanability and drainability. These compact assemblies are especially advantageous in pharmaceutical, biotech, and high-purity processing facilities where sanitation, validation, and minimal dead legs are critical. Reach out for custom configurations engineered to meet your exact process needs.

Actuation Options for ITT Pure-Flo & EnviZion Valves

• ITT Pure-Flo and EnviZion diaphragm valves are available in both manual and pneumatic actuation options, giving processors the flexibility to match each valve to its specific application, space constraints, and automation needs.

ADVANTAGE 2.1 ACTUATOR

• The Advantage 2.1 actuator is the core pneumatic actuator platform for Pure-Flo valves and represents a major leap forward in bioprocess valve performance. Its patent-pending compressor design allows interchangeability between PTFE and elastomer diaphragms without disassembling the actuator, dramatically reducing maintenance time and improving operational efficiency. Compact and lightweight, the Advantage 2.1 fits the tight space constraints common in pharmaceutical and biotech systems and is available in multiple closure modes for maximum application flexibility.

33 SERIES AND ACS STAINLESS ACTUATORS OPTIONS ALSO AVAILABLE

Manual Actuation: Reliable, Cleanable Design

• Manual diaphragm valve operators are available across the Pure-Flo and EnviZion product lines for applications requiring straightforward, operator-controlled flow regulation. These handwheel-style actuators maintain full cleanability, ergonomic operation, and durable construction — making them ideal for sampling points, low-cycle operations, or utility service.

Designed for Flexibility Across Pure-Flo and EnviZion

• Regardless of actuator choice, all ITT platforms pair seamlessly with Pure-Flo and EnviZion valve bodies, offering:
  • Streamlined installation
  • Hygienic, cleanable designs
  • Compatibility with high-purity processing standards
  • Support for both automated and manual control strategies
• Together, these actuation options deliver the performance, reliability, and flexibility required for today’s demanding pharmaceutical, biotech, food, and high-purity processing systems.